Calendar
Upcoming events
Advanced Computational Workshop
University of Illinois Urbana-Champaign
Contact name: Center for Quantitative Cell Biology
Contact email: qcb@beckman.illinois.edu
Diverse experimental data characterizing the cellular state and processes of the synthetic genetically minimal bacterial cell, JCVI-Syn3A, have been integrated into 4DWCM simulations of its time dependent cell states. Dynamics of the cell states and biomolecules are described at the composite particle level using Lattice Microbes, at the coarse-grained atomistic level using Martini/GROMACS, and at the all atom level using NAMD2 and GROMACS. For each representation, visualization is performed using VMD. The workshop will demonstrate how each computational method is performed on Syn3A and how information is passed between each program.
This workshop is targeted to those who have been using computational tools for a while and want to increase their knowledge and skills. It is not for beginners. Familiarity with one or more of the programs and python is required for participation. Agenda and registration here.
QCB Seminar - Margaret S. Cheung, PNNL
Beckman 3269 3rd Floor Tower Room
Title:
NW-BRaVE for Biopreparedness: Enhancing biopreparedness through a model system to understand the molecular mechanisms that lead to pathogenesis and disease transmissionAbstract:
In my presentation, I will provide a current update on a recently awarded project, NW-BRaVE, by the Department of Energy Office of Science in response to the National Biopreparedness Initiative. The science of biopreparedness to counter biological threats hinges on understanding the fundamental principles and molecular mechanisms that lead to pathogenesis and disease transmission. NW-BRaVE’s vision to address this challenge is to create a powerful and user-friendly platform to elucidate the fundamental principles of how molecular interactions drive pathogen-host relationships and host shifts. We will enable groundbreaking discoveries by integrating a wide range of structural, genomics, proteomics, and other advanced omics measurements, along with evolutionary and artificial intelligence predictions. To make sure the system is applicable to real-world problems, it will be developed in the context of a tractable model system, the small, abundant, and accessible photosynthetic cyanobacteria and their constantly co-adapting viral pathogens, cyanophages. This model will maintain the system’s applicability to real-world problems and techniques, but the overall focus will be on elucidating general principles of detecting, assessing, and surveilling molecular interaction, adaptation, and coevolution that are system agnostic and therefore extensible to any other viral-host interaction. The impact of the project will be to develop, implement, and test a platform to assess host-pathogen molecular interactions, adaptation to hosts and host shifts, and coevolution between hosts and pathogens. This ability will be critical for designing early interventions to address future threats.
QCB External Advisory Board
Inaugural meeting of the QCB External Advisory Board via Zoom. An invitation only event.
Midwest Advanced MINFLUX and Super Resolution Workshop
Carl R. Woese Institute for Genomic Biology
Contact name: Chris Zwilling
Contact email: zwillin1@illinois.edu
The NSF Science and Technology Center for Qualitative Cell Biology is hosting a Midwest Advanced MINFLUX and Super Resolution Workshop. The workshop will highlight STED and MINFLUX technology through talks and hands-on sessions with the MINFLUX and STEDYCON system.
NSF Site Visit
Beckman Institute
Contact name: Center for Quantitative Cell Biology
Contact email: qcb@beckman.illinois.edu
This meeting is only for QCB members and invited guests.
QCB Summer School
UIUC
More information coming soon!